Prednisone

Prednisone is a steroid that prevents the release of substances in the body that cause inflammation. 

Indications: 

1. Myasthenia Gravis

2. CIDP

3. Inflammatory Myopathies such as dermatomyositis, necrotizing myopathy, polymyositis etc.

4. Lambert Eaton Myasthenic Syndrome

5. Other  inflammatory Neuropathies

Side effects: 

High blood pressure

High blood sugar

Gastrointestinal upset

Mood fluctuation

Osteoporosis/Osteopenia

Cushingoid appearance

Following things to be pursued while being on prednisone……

1. Vitamin D supplements

2. Let your doctor know if you have gastrointestinal upset

3. Low salt diet

4. Low sugar diet

Low Salt Diet

Most people eat much more sodium (salt) than they need. This can lead to health problems like high blood pressure. To lower the amount of sodium in your diet, follow these tips when you go food shopping:

Low Sugar Diet

The average adult consumes about 22 teaspoons of added sugar a day. And that’s on top of any naturally occurring sugars consumed through fruit, grains, and milk products. Excessive sugar consumption has been linked to: obesity, diabetes, heart disease, increased inflammation in the body, high cholesterol, and high blood pressure.

Prednisone

Prednisone is used to treat many different inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, allergic disorders, gland (endocrine) disorders, and conditions that affect the skin, eyes, lungs, stomach, nervous system, or blood cells.

IVIG

Intravenous immune globulin (“IVIG”) is a product made up of antibodies that can be given intravenously (through a vein). IVIG is given into a vein (“intravenously”), in an infusion that takes one hour or more. The amount of IVIG you need for each dose depends on your weight as well as the reason you are getting the IVIG:

Plasmapheresis/Apheresis

Plasmapheresis/Apheresis is a process in which the fluid part of the blood, called plasma, is removed from blood cells by a device known as a cell separator. The separator works either by passing the blood at high speed to separate the cells from the fluid or by passing the blood through a membrane with pores so small that only the fluid part of the blood can pass through. 

Eculizumab

Eculizumab is the first treatment to be approved to treat adults with anti-AChR Ab+ gMG in more than 60 years. Soliris works to help manage anti-acetylcholine receptor antibody-positive generalized Myasthenia Gravis (anti-AChR Ab+ gMG) by focusing on a specific part of your immune system.

Rituximab

Rituximab is a genetically engineered antibody that depletes CD20+ B-cells and is Food and Drug Administration- approved for treatment of non-Hodgkin lymphoma, CD20+ CLL, and rheumatoid arthritis. It carries a favorable side effects profile. 

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